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CAMELLIA SINENSIS (GREEN TEA) EXTRACT (50% polyphenol
content) contains potent antioxidant compounds that have demonstrated greater antioxidant
protection than vitamins C and E in experimental studies as well as exhibit anti-allergy
activity.1,2 Green tea extract is also rich in Theophylline, a compound used as
a prescription drug in the treatment of asthma.3
The polyphenols in camellia sinensis have also been
shown to stimulate the production of several immune system cells, and have antibacterial
properties - even against the bacteria that cause dental plaque.4,5,6 In fact,
the polyphenols are believed to be responsible for most of green tea's role in promoting
good health.7
Green tea polyphenols inhibit cancer by blocking the
activation of carcinogens, and detoxifying or trapping cancer-causing compounds such as
nitrosamines, suppressing the activation of carcinogens, and detoxifying or trapping
cancer-causing agents. The forms of cancer that appear to be best prevented are cancers of
the gastrointestinal tract, the stomach, small intestine, pancreas, colon, lung cancer,
and estrogen-related cancers including most breast cancers8,9
Camellia sinensis guards against cardiovascular disease
by lowering total cholesterol levels while improving the cholesterol profile of LDL to HDL
cholesterol and lowering blood pressure.10,11
BERBERIS ALKALOID EXTRACT containing the major
alkaloid, berberine, has been extensively studied in clinical settings. Berberine has
shown antibiotic activity against bacteria, protozoa, and fungi, including Staphylococcus
species, Streptomyces species, Corynebacterium diphtheria, E. coli, salmonella
typhi,
Diplococcus pneumoniae, Trichomonas vaginalis, N. meningitidis, and Candida albicans.12,13,14
Berberine has the ability to inhibit the adherence of
streptococci to host cells. Simply stated, berberine interferes with infections due to
streptococci not only by inhibiting streptococcal growth, but also by blocking these
organisms to host cells.15
Berberine has been found effective against diarrheas
caused by E. coli (traveler's diarrhea), Shigella dysenteriae (shigellosis), Salmonella
paratyphi (food poisoning), and Vibrio cholerae (cholera). Clinical studies have produced
results with berberine comparable to those of standard antibiotics in most cases, and in
several studies results were actually superior.16,17,18
ECHINACEA
(ANGUSTIFOLIA) EXTRACT activates a part of
the immune system known as the alternate complement pathway. As a result, the movement of
white blood cells into areas of infection is enhanced; immune complexes
solubilize; and
bacteria, viruses and other microorganisms are destroyed.19,20
Echinacea elevates serum white blood cell counts when
they are low, including T lymphocytes, or T cells.21 These cells are a type of
white blood cell responsible for "cell-mediated immunity" which refers to immune
mechanisms not controlled or mediated by antibodies. This is extremely important in
providing resistance to infection by mold-like bacteria, yeast, fungi, parasites, and
viruses including those that cause hepatitis.22,23
Cell-mediated immunity is also critical in protecting
against the development of cancer, autoimmune disorders such as rheumatoid arthritis, and
allergies. Echinacea has been successfully utilized to treat all of these conditions.24
Echinacea extract stimulates stem cells in bone marrow
and lymphatic tissue where immune system cells are produced, and increase the number and
activity of these cells in the blood and lymphatic circulation.25
It has been stated that Echinacea is one of the most
powerful and effective remedies against bacteria and viral infections.26
PANAX GINSENG ROOT EXTRACT (standardized to 5%
ginsenosides) exerts numerous pharmacological effects including antistress activity,
improved endocrine system function, enhanced protein synthesis and cell reproduction;
improved glucose control in diabetics; lowering of serum cholesterol; and protection of
the liver from toxic substances.27,28,29,30
Ginseng possesses immunostimulating activity as
evidenced by its ability to enhance antibody responses, cell-mediated immunity and the
production of interferon.31
Ginseng also has the ability to enhance the activity of
the cells of the reticuloendothelial system. This system is composed of white blood cells
known as macrophages, which filter the blood and lymph by engulfing and destroying
bacteria, viruses, and other waste matter. Such macrophages are found in highest
concentrations in the liver, spleen, and lymph nodes.32
The liver contains specialized macrophages known as
Kupffer cells. Ginseng stimulates and increases the activity of these cells which are
responsible for removing toxins and debris from the circulation.33 Ginseng has
also been demonstrated to increase protein synthesis in the liver which is often reduced
in the elderly.34
Clinical studies have shown that ingestion of ginseng
by individuals with mild immune deficiency (frequent colds) may reduce the risk of viral
infection.35
USNEA (USNEA BARBATA) contains usnic acid which acts as an antibiotic. Unlike
other antibiotics which disrupt structural components of bacterial cells, usnea
kills microbes by disrupting cellular metabolism. Also, unlike synthetic
antibiotics which kill the natural flora in the vagina and gut, usnea does not
destroy "friendly" bacteria and therefore does not adversely affect the body's
natural ecology.36
Usnea has been found to be especially effective for acute bacterial infections.
Many individuals have also had great success using usnea for sinusitis,
bronchitis, pneumonia, and colds when nothing else had worked.37
OCIMUM BASILICUM exhibits in vitro antibacterial
activity against Bacillus subtilis, E. coli, Pseudomonas auerginosa, and Staphylococcus
aureus. Strong activity was also shown against Candida albicans.38
Ocimum basilicum is also a galactagogue and
stomachic.
It is useful for stomach cramps, gastric catarrh, vomiting and intestinal catarrh which
are symptoms usually associated with colds, flu, and similar virus ailments.39
ROSMARINUS OFFICINALIS contains some of the most
powerful candida killing substances available.40 The active constituents of
this herb include eucalyptol which exhibits antibacterial effects41 and relaxes
smooth muscles in the lungs.42 Rosmarinic acid has significant antioxidant
activity.43
The stimulant action of rosemary helps promote liver
function, the production of bile, and proper digestion. It also acts to improve
circulation.44
GARLIC EXTRACT (from 66 mg fresh garlic) were found to
be effective antibiotic agents against many bacteria, including Staphylococcus
aureus,
Escherichia coli, salmonella enteritidis, Klebsiella pneumoniae, and mycobacteria.45,46,47
These studies compared the antimicrobial effects of garlic with those of commonly used
antibiotics, including penicillin, streptomycin, chloramphenicol, erythromycin, and
tetracyclines. These studies demonstrated garlic's efficacy in inhibiting the growth of
some bacteria that had become resistant to one or more of the antibiotics.
Garlic possesses important immune-enhancing and
anticancer properties. Human studies show that garlic inhibits the formation of
nitrosamines which are powerful cancer-causing compounds formed during digestion.48
Garlic has demonstrated significant antifungal activity
against a wide range of fungi. Garlic is especially active against C. albicans, being more
potent than Nystatin and six other reputed antifungal agents.49
Garlic's antiviral effects have been well studied. In
vitro, fresh garlic killed herpes simplex types 1 and 2, para-influenza virus type 3,
vesicular stomatitis virus, and human rhinovirus type 2. Fresh garlic extract was
virucidal against all viruses tested but the virucidal activity of commercial products
depended how they were prepared. Those products producing the highest level of allicin and
other thio-sulfinates, such as found in Factor Twelve: Opti-cillin, had the best virucidal
activity.50
Based on clinical research, the dosage of a commercial
garlic product should provide a daily dose of 4 mg of allicin.51
CHOROPHYLLIN (pure) is "natures deodorant"
and aids in cleansing of the bloodstream.52 According to G. W. Rapp in the
American Journal of Pharmacy, chorophyllin also possesses positive antibacterial action
and reduces the hazard of bacterial contamination. It's main purpose in this formulation,
however, is to off-set some of the more pungent herbal extracts utilized in Factor Twelve:
Opti-cillin.
FACTOR
TWELVE FORMULATION
Two Tablets Equal:
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Camellia
sinensis extract (50% polyphenol content)
Berberis alkaloid extract equal to
Echinacea (angustifolia) extract equal to
Panax Ginseng root extract (5% ginsenosides) equal to
Usnea (Usnea barbata)
Ocimum basilicum
Rosmarinus officinalis
Garlic extract (from 66 mg fresh garlic)
Chorophylllin (pure)
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360 mg
275 mg
250 mg
200 mg
100 mg
100 mg
35 mg
4 mg
1 mg
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